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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2015.6
- 수록면
- 81 - 94 (14page)
이용수
초록· 키워드
오류제보하기
Depression is one of the most common psychiatric disorders that is associated with high level of disability, morbidity and mortality. Depression is a heterogeneous disorder, and it seems to be the result of complex interaction of several factors including genetic and environmental factors. Numerous studies have reported available biomarkers in depression, which is detectable biological character reflecting pathogenic process or treatment response. They include neuroendocrine system such as hypothalamic-pituitary-adrenal axis, inflammatory markers, neurotrophic factors, fatty acid markers, sleep factors, structural brain images and functional brain images. Understanding biomarkers is essential for classifying the clinical features of depression and subsequently help determine individualized treatment for each subgroup. This article reviewed literatures about biomarkers in depression, in order to reconsider potential clinical use of it.
목차
서론
신경내분비 체계(Neuroendocrine Systems)
염증 인자들(Inflammatory Markers)
지방산 인자(Fatty Acid Markers)
신경영양적 인자(Neurotrophic Factors)
수면(Sleep)
구조적 뇌영상(Structural Brain Images)
기능적 뇌영상(Functional Brain Images)
우울증 생체 지표의 통합적인 모델(Integrative Model of Biomarkersin Depression)
우울증 생체 지표의 임상적인 이용(Clinical Application of Biomarkersfor Depression)
결론
참고문헌
참고문헌 (160)
참고문헌 신청
[단행본] - Sadock BJ / 2007 / Synopsis of psychiatiry / Lippincott Williams & Wilkins
[학술지(정기간행물)] - Kessler RC / 2005 / Lifetime prevalence and age-of-onset distributions of DSM-IV disorders in the national comorbidity survey replication / Arch Gen Psychiatry 62 : 593 ~ 602
[학술지(정기간행물)] - Palazidou E / 2012 / The neurobiology of depression / Br Med Bull 101 : 127 ~ 145
[학술지(정기간행물)] - Maletic V / 2007 / Neurobiology of depression: an integrated view of key findings / Int J Clin Pract 61 : 2030 ~ 2040
[학술지(정기간행물)] - Marije aan het Rot M / 2009 / Neurobiological mechanisms in major depressive disorder / CMAJ 180 : 305 ~ 313
[학술지(정기간행물)] - Kessler RC / 2005 / Lifetime prevalence and age-of-onset distributions of DSM-IV disorders in the national comorbidity survey replication / Arch Gen Psychiatry 62 : 593 ~ 602
[학술지(정기간행물)] - Palazidou E / 2012 / The neurobiology of depression / Br Med Bull 101 : 127 ~ 145
[학술지(정기간행물)] - Maletic V / 2007 / Neurobiology of depression: an integrated view of key findings / Int J Clin Pract 61 : 2030 ~ 2040
[학술지(정기간행물)] - Marije aan het Rot M / 2009 / Neurobiological mechanisms in major depressive disorder / CMAJ 180 : 305 ~ 313
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UCI(KEPA) : I410-ECN-0101-2016-513-001657488